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Covalent organic frameworks assembled inside tumor cells trigger cancer cell death and immune activation

Feb 26, 2026 Crystalline polymers assembled inside tumor cell lysosomes rupture membranes, release iron, and trigger immune-activating ferroptosis that shrinks tumors in mice. (Nanowerk Spotlight) Cells produce natural polymers such as DNA, proteins, and sugars to sustain life. Synthetic polymers can offer properties they lack: customizable architecture, tunable porosity, built-in...